The Human SOX11 Gene: Cloning, Chromosomal Assignment and Tissue Expression
Identifieur interne : 00D480 ( Main/Exploration ); précédent : 00D479; suivant : 00D481The Human SOX11 Gene: Cloning, Chromosomal Assignment and Tissue Expression
Auteurs : Philippe Jay [France] ; Catherine Gozé [France] ; Catherine Marsollier [France] ; Sylvie Taviaux [France] ; Jean-Pierre Hardelin [France] ; Peter Koopman [Australie] ; Philippe Berta [France]Source :
- Genomics [ 0888-7543 ] ; 1995.
English descriptors
- KwdEn :
- Academic press, Acidic domain, Amino acid sequence, Amino acids, Binding domain, Black edges, Cdna, Chicken homologue, Ecori fragment, Expression pattern, Gene, Gene family, Genomic clone, Homologue, Human sox4, Hybridization, Nervous system, Nucleic, Nucleic acids, Oligonucleotide probe, Probe, Reading frame, Short communication, Striking feature, Transcription factors.
- Teeft :
- Academic press, Acidic domain, Amino acid sequence, Amino acids, Binding domain, Black edges, Cdna, Chicken homologue, Ecori fragment, Expression pattern, Gene, Gene family, Genomic clone, Homologue, Human sox4, Hybridization, Nervous system, Nucleic, Nucleic acids, Oligonucleotide probe, Probe, Reading frame, Short communication, Striking feature, Transcription factors.
Abstract
Abstract: The mammalian testis determining gene SRY contains an HMG box-related DNA binding motif. By analogy a family of genes related to SRY in the HMG domain have been called SOX (SRY box-related genes). We have cloned and characterized the human SOX11 gene using the partial cloning of both human and mouse SOX11 genes and mapped it to chromosome 2p25. The SOX11 sequence is strongly conserved with the chicken homologue and is related to SOX4. It contains several putative transcriptional either activator or repressor domains. SOX11 expression pattern is consistent with the hypothesis that this gene is important in the developing nervous system.
Url:
DOI: 10.1006/geno.1995.9970
Affiliations:
- Australie, France
- Languedoc-Roussillon, Occitanie (région administrative), Île-de-France
- Montpellier, Paris
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000253
- to stream Istex, to step Curation: 000253
- to stream Istex, to step Checkpoint: 002757
- to stream Main, to step Merge: 00E681
- to stream Main, to step Curation: 00D480
Le document en format XML
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system</term><term>Nucleic</term><term>Nucleic acids</term><term>Oligonucleotide probe</term><term>Probe</term><term>Reading frame</term><term>Short communication</term><term>Striking feature</term><term>Transcription factors</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The mammalian testis determining gene SRY contains an HMG box-related DNA binding motif. By analogy a family of genes related to SRY in the HMG domain have been called SOX (SRY box-related genes). We have cloned and characterized the human SOX11 gene using the partial cloning of both human and mouse SOX11 genes and mapped it to chromosome 2p25. The SOX11 sequence is strongly conserved with the chicken homologue and is related to SOX4. It contains several putative transcriptional either activator or repressor domains. SOX11 expression pattern is consistent with the hypothesis that this gene is important in the developing nervous system.</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Languedoc-Roussillon</li><li>Occitanie (région administrative)</li><li>Île-de-France</li></region><settlement><li>Montpellier</li><li>Paris</li></settlement></list><tree><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Jay, Philippe" sort="Jay, Philippe" uniqKey="Jay P" first="Philippe" last="Jay">Philippe Jay</name></region><name sortKey="Berta, Philippe" sort="Berta, Philippe" uniqKey="Berta P" first="Philippe" last="Berta">Philippe Berta</name><name sortKey="Goze, Catherine" sort="Goze, Catherine" uniqKey="Goze C" first="Catherine" last="Gozé">Catherine Gozé</name><name sortKey="Hardelin, Jean Pierre" sort="Hardelin, Jean Pierre" uniqKey="Hardelin J" first="Jean-Pierre" last="Hardelin">Jean-Pierre Hardelin</name><name sortKey="Marsollier, Catherine" sort="Marsollier, Catherine" uniqKey="Marsollier C" first="Catherine" last="Marsollier">Catherine Marsollier</name><name sortKey="Taviaux, Sylvie" sort="Taviaux, Sylvie" uniqKey="Taviaux S" first="Sylvie" last="Taviaux">Sylvie Taviaux</name></country><country name="Australie"><noRegion><name sortKey="Koopman, Peter" sort="Koopman, Peter" uniqKey="Koopman P" first="Peter" last="Koopman">Peter Koopman</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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